5-Methylindole-3-Carbocylic acid methyl ester

5-Methylindole-3-Carbocylic acid methyl ester - Names and Identifiers

Name	Methyl 5-methylindole-3-carboxylate
Synonyms	RARECHEM AL BF 0707 Methyl 5-methylindole-3-carboxylate methyl 5-methyl-1H-indole-3-carboxylate METHYL 5-METHYL-1H-INDOLE-3-CARBOXYLATE 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER 5-Methylindole-3-Carbocylic acid methyl ester 5-Methylindole-3-carboxylic acid methyl ester 1H-Indole-3-carboxylicacid,5-Methyl-,Methylester 5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
CAS	227960-12-5
EINECS	607-884-2
InChI	InChI=1/C11H11NO2/c1-7-3-4-10-8(5-7)9(6-12-10)11(13)14-2/h3-6,12H,1-2H3

5-Methylindole-3-Carbocylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C11H11NO2
Molar Mass	189.21
Density	1.212±0.06 g/cm3(Predicted)
Boling Point	345.1±22.0 °C(Predicted)
Flash Point	162.5°C
Vapor Presure	6.28E-05mmHg at 25°C
pKa	15.59±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.624

5-Methylindole-3-Carbocylic acid methyl ester - Introduction

Methyl 5-methylindole-3-carboxylate is an organic compound with the chemical formula C12H11NO2.

Nature:
-Appearance: colorless liquid
-Boiling point: About 245-250 ℃
-Melting point: About 15-18 ℃
-Solubility: Soluble in most organic solvents, such as ethanol, ether and acetone

Use:
- Methyl 5-methylindole-3-carboxylate is widely used in drug synthesis as an important intermediate for the synthesis of indole derivatives.
-It is an important raw material for organic synthesis, which can be used to synthesize drugs, pesticides and other organic compounds.

Method:
- Methyl 5-methylindole-3-carboxylate can be prepared by the following reaction:
1.5-methyl indole and bromoacetate are reacted to generate 5-methyl indole -3-ester.
2.5-Methyl indole-3-ester and methanol are transesterified in the presence of a catalyst to generate Methyl 5-methylindole-3-carboxylate.

Safety Information:
- Methyl 5-methylindole-3-carboxylate is a chemical that is potentially dangerous.
-Avoid contact with skin, eyes and respiratory tract during use.
-Please use in a well-ventilated place and wear appropriate protective equipment, such as gloves and goggles.
-If inhaled or taken by mistake, consult a doctor immediately and show the relevant chemical label or safety data sheet to the doctor.

Last Update：2024-04-09 02:00:44